L-744832(CAS:1177806-11-9)(分子式:C26H47Cl2N3O6S2)
产品名称: L-744832(CAS:1177806-11-9)(分子式:C26H47Cl2N3O6S2)
英文名称: L-744832
产品编号: TRC-L744832
产品价格: 0
产品产地: CANADA
品牌商标: TRC
更新时间: null
使用范围: null
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1) Cat. No.: TRC-L744832; 2) Chemical Name: L-744832; 3) CAS No.: 1177806-11-9; 4) Mol. Formula: C26H47Cl2N3O6S2; 5) Mol. Weight: 632.7; 6) Packing Size: 5mg / 50mg; 7) Appearence: White Solid; 8) Application Notes: Ras farnesyltransferase inhibitor. Induces tumor regression in transgenic mice with multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis. Induces p21 expressoin and arrests cells at G1. Causes enhanced mitotic sensitivity to taxol.; 9) Synonym: (2S)-[(2S)-[(2R)-Amino-3-mercapto]-propylamino-(3S)-methyl]pentyloxy-3-phenylpropionyl-methionine Sulfone Isopropyl Ester Bis Hydrchloride;; 10) Solubility: Acetonitrile, Methanol; 11) Storage condition: -20°C Freezer; 12) References: Barrington, R.E., et al.: Mol. Cell. Biol., 18, 85 (1998, Sepp-Lorenzo, L. and Rosen, N.: J. Biol. Chem., 273, 20243 (1998), Moasser, M.M., et al.: Proc. Natl. Acad. Sci. USA, 95, 1369 (1998), Law, B.K., et al.: J. Biol. Chem., 275, 10796 (2000),